Johannes Kepler Symposium für Mathematik

Im Rahmen des Johannes-Kepler-Symposiums für Mathematik wird Prof. Dr. Gabriel Wittum, Goethe Center for Scientific Computing (G-CSC), Goethe University Frankfurt, am Fri, July 6, 2012 um 13:45 Uhr im HS 9 einen öffentlichen Vortrag (mit anschließender Diskussion) zum Thema "Modelling and Simulation of Biological Systems" halten, zu dem die Veranstalter des Symposiums,

O.Univ.-Prof. Dr. Ulrich Langer,
Univ.-Prof. Dr. Gerhard Larcher
A.Univ.-Prof. Dr. Jürgen Maaß, und
die ÖMG (Österreichische Mathematische Gesellschaft)

hiermit herzlich einladen.

Series B - Mathematical Colloquium:

The intention is to present new mathematical results for an audience interested in general mathematics.

Modelling and Simulation of Biological Systems

Biological systems are distinguished by their enormous complexity and variability. That is why mathematical modelling and computational simulation of those systems is very difficult, in particular thinking of detailed models which are based on first principles. The difficulties start with geometric modelling which needs to extract basic structures from highly complex and variable phenotypes, on the other hand also has to take the statistic variability into account. Moreover, the models of the processes running on these geometries are not yet well established, since these are equally complex and often couple many scales in space and time. Thus, simulating such systems always means to put the whole frame to test, from modelling to the numerical methods and software tools used for simulation. These need to be advanced in connection with validating simulation results by comparing them to experiments.

To treat problems of this complexity, novel mathematical models, methods and software tools are necessary . In recent years, such models, numerical methods and tools have been developed, allowing to attack these problems. In the talk we consider two examples as paradigms for the process of modelling and simulation in biosciences. The first example is the diffusion of xenobiotics through human skin, the second one is the automatic reconstruction of neurons and nueclei by means of numerical methods for partial differential equations.